16S RRNA ANALYSIS OF MICROBIOTA COMPOSITION AGAINST THE BACKGROUND OF SARS-COV-2 INFECTION USING MOLECULAR DIAGNOSTICS (LITERATURE REVIEW)

Authors

  • Sobirjon T. Jumamurodov
  • Zukhra A. Nuruzova

Keywords:

SARS-CoV-2, COVID-19, microbiota, 16S rRNA sequencing, molecular diagnostics, microbiota dysbiosis, immune system, molecular biology.

Abstract

This article is devoted to the study of microbial environmental changes against the background of SARS-CoV-2 infection using molecular diagnostics. The composition of the human microbiota was analyzed using 16S rRNA sequencing technology and the dysbiosis of the microbiota associated with COVID-19 was studied. The article presents scientific data on the enrichment or reduction of the microbiota with different categories of microorganisms during SARS-CoV-2 infection, as well as their impact on health and the immune system. The clinical implications of changes in the structure of the microbiota and the possibility of their application for diagnostic purposes have also been considered.

Author Biographies

Sobirjon T. Jumamurodov

PhD candidate of the Department of Microbiology, Virology and Immunology, Tashkent Medical Academy, Tashkent, Uzbekistan

E-mail: sobirjonjumomurodov@gmail.com

Zukhra A. Nuruzova

Professor of the Department of Microbiology, Virology and Immunology,
Tashkent Medical Academy, Tashkent, Uzbekistan

E-mail: voyna_microbam@mail.ru

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Published

2025-02-05

How to Cite

Sobirjon T. Jumamurodov, & Zukhra A. Nuruzova. (2025). 16S RRNA ANALYSIS OF MICROBIOTA COMPOSITION AGAINST THE BACKGROUND OF SARS-COV-2 INFECTION USING MOLECULAR DIAGNOSTICS (LITERATURE REVIEW). Central Asian Journal of Medicine, (1), 166-173. Retrieved from https://journals.tma.uz/index.php/cajm/article/view/1004

Issue

No. 1 (2025): CAJM

Section

Articles