ANALYSIS OF INFLAMMATORY DISEASES OF THE THROAT AND THE ANTIBIOTICS USED IN THEM
Keywords:
upper respiratory tract inflammation, throat inflammation, bacteria, antibiotics, microorganisms, tonsillopharyngitis, acute tonsillitis, acute pharyngitis.Abstract
Research objective: To determine the etiology of throat diseases in the population of the Republic of Uzbekistan in 2023-2024 and to describe their antibiotic resistance status. Materials and methods: The infections detected in patients with throat infections from the second half of 2023 to the beginning of 2024 at the Bacteriological Laboratory of the Tashkent Medical Academy of the Republic of Uzbekistan, as well as the microorganisms identified in them and their antibiotic sensitivity were analyzed. Bacteriological and statistical methods were used. Analysis and discussion of results: During this 6-month period, 200 patients (25 men, 175 women) complained of inflammatory diseases in the throat. When samples taken from them were laboratory diagnosed, more than 400 different bacteria were detected in all patients (Streptococcus ssp.-60%, Candida ssp.-30%, Staphylococcus aureus-10%). Conclusion: As a result of the analysis, we can see that women are more likely to get sore throats (88%) (average age was 27). The most common cause of inflammation is Streptococcus ssp (60%), and the most effective antibiotics for the bacteria: Sulfamethoxazole, Levofloxacin, Amoxicillin and Ampicillin gave good results.
References
Ana Moragasa, Carolina Sarvise, Frederic Gomeza, Ester Pico-Planae, Silvia Crispid, Carl Llorb. Duration of severe and moderate symptoms in pharyngitis by cause. https://doi.org/10.1016/j.aprim.2024.102994
B. Elmas, M. Koroglu, H.A. Terzi, F.G. Aslan, E. Menekse, M. Kosecik, M. Altindis. Acute exudative tonsillopharyngitis; Epstein-Barr virus, Herpesvirus and Adenovirus. http://dx.doi.org/10.1016/j.jcv.2016.08.280
Dr Yohance Rodriguez, Dr Camille-Ann Thoms Rodriguez, Professor J Peter Figueroa. Antibiotic Over-prescribing in the Treatment of Pharyngitis Among Clinicians in Jamaica. https://doi.org/10.1016/j.ijid.2024.107488
Fatih Mehmet Yazar, Murat Bakacak, Arif Emre, Aykut Urfaloglu, Salih Serin, Emrah Cengiz, Ertan Bulbuloglu. Predictive role of neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios for diagnosis of acute appendicitis during pregnancy. http://dx.doi.org/10.1016/j.kjms.2015.10.005
Guntinas-Lichius, Orlando, Geissler, Katharina, Makitie, Antti, Ronen, Ohad, Bradley, Patrick, Rinaldo, Alessandra, Takes, Robert, Ferlito, Alfio. Treatment of recurrent acute tonsillitis-a systematic review and clinical practice recommendations. https://doi.org/10.3389/fsurg.2023.1221932
Josep M. Cots, Juan-Ignacio Alos, Mario Barcena, Xavier Boleda, Jose L. Canada, Niceto Gomez, Ana Mendoza, Isabel Vilaseca, Carles Llori. Recommendations for Management of Acute Pharyngitis in Adults. ivila@clinic.ub.es
Olli Ruuskanen, Maarit Valtonen, Matti Waris, Raakel Luoto, Olli J. Heinonen. Sport and exercise during viral acute respiratory illness-Time to revisit. https://doi.org/10.1016/j.jshs.2023.12.002
Osiejewska Aleksandra, Gorajek Anna, Kudan Malgorzata, Gradzik Anna, Mikut Karolina. Acute tonsillopharyngitis - a review. Journal of Education, Health and Sport. 2022;12(7):873-882. eISSN 2391-8306. DOI http://dx.doi.org/10.12775/JEHS.2022.12.07.087
Pellegrino, R., Timitilli, E., Verga, M.C. et al. Acute pharyngitis in children and adults: descriptive comparison of current recommendations from national and international guidelines and future perspectives. Eur J Pediatr 182, 5259-5273 (2023). https://doi.org/10.1007/s00431-023-05211-w
Prakash Chand Negia, Rajeev Merwaha, Shivani Rao, Sanjeev Asotra, Anjali Mahajan, Ashish Joshib. School-based surveillance for detection of children with acute pharyngitis, rheumatic fever/rheumatic heart disease in Shimla district, Himachal Pradesh, India-A cluster randomized controlled trial. https://doi.org/10.1016/j.ihj.2018.05.015
Rebecca Buttner, Melanie Schwermer, Thomas Ostermann, Alfred Langler, Tycho Zuzak. Complementary and alternative medicine in the (symptomatic) treatment of acute tonsillitis in children: A systematic review. https://doi.org/10.1016/j.ctim.2023.102940
S. R. Norrby, J. Quinn, M. Rangaraju and B. Leroy. Evaluation of 5-day therapy with telithromycin, a novel ketolide antibacterial, for the treatment of tonsillopharyngitis. 2004 Copyright by the European Society of Clinical Microbiology and Infectious Diseases
Samuel Prasetyo, Ika Susilastining Utami, General Practitioner Ngudi Waluyo General Hospital Wlingi Blitar, Department of Otorhinolaryngology Ngudi Waluyo General Hospital Wlingi Blitar. Pattern of Pharyngitis and Tonsillitis Patients at ENT Clinic of Wlingi Hospital in 2019-2021. https://doi.org/10.21776/ub.jkb.2022.032.03.8
Singh H, Bhatt A, Kumar M, Deshmukh P. Tonsillitis and Sinusitis: A Narrative Review of Pathogenesis, Diagnosis, and Management. Cureus. 2023 Oct 17;15(10):e47192. doi: 10.7759/cureus.47192. PMID: 38021555; PMCID: PMC10652663.
William Nseir, Julnar Mograbi, Zuhair Abu-Rahmeh, Mahmud Mahamid, Omar Abu-Elheja, Adel Shalata. The association between vitamin D levels and recurrent group A streptococcal tonsillopharyngitis in adults. http://dx.doi.org/10.1016/j.ijid.2012.05.1036
