DYNAMICS OF NT-PROBNP PROTEIN STATE IN CHILDREN WITH CONGENITAL HEART DEFECTS

Authors

  • Khaydarov K.I., Usmanova D.U. Tashkent Pediatric Medical Institute (Tashkent, Uzbekistan)
  • Khamraeva G.Sh. Center for the Development of Professional Qualifications of Medical Workers (Tashkent, Uzbekistan)

Keywords:

congenital heart defects, markers, brain natriuretic peptide, children.

Abstract

Significant scientific results aimed at studying diagnostic and prognostic measures in Pediatric Critical Care Medicine (2022) have shown that IL-6, IL-1beta, IL-10 and TNF-alpha levels correlate with the development of postoperative systemic inflammatory response syndrome (SIRS) and acute complications. IL-33 levels are considered as a potential prognostic marker for the risk of pulmonary hypertension and cardiac failure after CABG interventions. Elevated levels of high-sensitivity troponin and NT-proBNP are associated with an increased risk of postoperative cardiac dysfunction. ST2 (interleukin suppressor) has been proposed as a prognostic marker for death or prolonged ventilatory support in neonates after open heart surgery (Journal of Thoracic and Cardiovascular Surgery, 2023).

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Published

2025-10-02

How to Cite

Khaydarov K.I., Usmanova D.U., & Khamraeva G.Sh. (2025). DYNAMICS OF NT-PROBNP PROTEIN STATE IN CHILDREN WITH CONGENITAL HEART DEFECTS. Central Asian Journal of Medicine, (6). Retrieved from https://journals.tma.uz/index.php/cajm/article/view/1494

Issue

No. 6 (2025): CAJM

Section

Articles