THE STUDY OF THE EFFECT OF RADIATION AND CHEMOTHERAPY ON THE FUNCTION OF THE HEART
No. 3 (2023), Articles
No. 3 (2023)

THE STUDY OF THE EFFECT OF RADIATION AND CHEMOTHERAPY ON THE FUNCTION OF THE HEART

Articles
Published 2023-10-04
Zavqiddin M. Kenjaev
Bukhara State Medical Institute
Lola Dj. Sultanova
Bukhara State Medical Institute
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Keywords

cardio taxicity, effect, radiation therapy, drugs.

How to Cite

Zavqiddin M. Kenjaev, & Lola Dj. Sultanova. (2023). THE STUDY OF THE EFFECT OF RADIATION AND CHEMOTHERAPY ON THE FUNCTION OF THE HEART. Central Asian Journal of Medicine, (3), 179-189. Retrieved from https://journals.tma.uz/index.php/cajm/article/view/700
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Abstract

The effect of chemoradiotherapy (CLT) on the cardiovascular system has been known since the 70s [4]. The dose-dependent cardiotoxicity of anthracycline antibiotic metabolites has been most well studied [6], which usually manifests itself already during treatment or in the first months and years after its completion.

 The most common of the early clinically significant cardiac complications of radiation therapy is effusion pericarditis. Lesions of the coronary arteries, valves, pericardial constriction and chronic heart failure (CHF), caused by progressive sclerotic changes in all structures of the heart, make their debut much later [3].

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