LOCAL IMMUNITY OF THE MOUTH IN PATIENTS WITH CHRONIC KIDNEY FAILURE HAVE OR HAVE NOT GEMODIALYSIS TREATMENT

Abstract

Evaluation of local oral immunity in patients with chronic renal failure receiving and not receiving
hemodialysis therapy. Materials and methods: This study was conducted in 108 patients. The formation of secretory
immunoglobulin in saliva was determined using the Vector Best kits (Russia). The data obtained were processed using
the program Statistics 6.0. Calculated mean arithmetic values (M) and standard deviations (m). Reliability factors
were calculated using Student’s t-test. Results: The studies of saliva of patients with chronic renal failure receiving
hemodialysis also showed a deficiency of lysozyme and sIgA. These indicators were significantly 1.4 times lower (P
<0.001) than in the healthy control group, and 1.7 times lower than in patients with chronic renal failure who did
not receive dialysis. It was found that PN in this group of patients was 46% and 53.3% higher than in the comparison
group. Conclusions: These features should be taken into account in the treatment of diseases of the oral cavity in
patients with chronic renal failure, especially in the case of prosthetics.