CLINICAL EFFICACY OF ENDOVASCULAR CORONARY REVASCULARIZATION IN PATIENTS WITH CORONARY ARTERY DISEASE WITH A LOW LV FRACTION ASSOCIATED WITH TYPE 2 DIABETES MELLITUS

Abstract

To conduct a comparative assessment of the clinical efficacy of endovascular coronary revascularization
in patients with coronary artery disease, with systolic heart failure with the presence/absence of type 2 diabetes mellitus
(DM). Materials and methods: The study included 60 patients with coronary heart disease with chronic heart failure IIIII
NYHA class and LVEF less than 45%, who were divided into two groups: Group 1 (n=30) included patients with type
2 diabetes. Group 2 (n=30) consisted of patients with absence of type 2 diabetes. All patients underwent angiographic
examination followed by revascularization et hoc. The data of a 6-minute walking test, scale clinical assessment (Mareev),
transthoracic echocardiographic (EchoCG) study, biochemical analyzes were evaluated. Results: It was shown that PCI in
patients with ischemic cardiomyopathy was characterized by an improvement in intracardiac hemodynamics, irrespective
of the presence/absence of type 2 diabetes with an increase in LVEF, a decrease in the ratios of EDV/LV mass and LA/EDD.
These changes were accompanied by clinical improvement in the form of a decrease in the total number of points on scale
(all p <0.05), an increase in the physical activity of patients, without significant differences between the groups. Biochemical
changes were reflected in a significant decrease in lipid fractions, sugar and glycated hemoglobin. Conclusions: A positive
effect of revascularization on the parameters of the contractility of the heart was noted, accompanied by a significant clinical
improvement. Moreover, the presence of type 2 diabetes does not significantly affect the results.