DYNAMICS OF CLINICAL AND DIAGNOSTIC PARAMETERS OF CEREBRAL BLOOD FLOW IN PATIENTS WITH HYPERTENSIVE ENCEPHALOPATHY ON THE BACKGROUND OF THE DRUG METAXAZ

Abstract

To assess the dynamics of clinical and diagnostic parameters of cerebral blood flow in patients with
hypertensive encephalopathy on the background of treatment with Metaxas. Materials and methods: 105 patients
of the neurological Department of the Regional Specialized Somatic hospital with a diagnosis of hypertensive
encephalopathy of various stages were examined cerebral hemodynamics, using the method of transcranial duplex
scanning of veins and sinuses of the brain and rheoencephalography. Then, out of 85 patients who had registered
diagnostic signs of cerebral venous dysfunction, two groups were formed, dividing the studied depending on the
method of treatment applicable in the future: with the inclusion of the drug Metaxase in complex therapy from day
1 to day 60 (the main group – 39 people) - and without it (the control group – 46 people). Control studies of cerebral
hemodynamics were performed in both groups on the 30th and 60th day from the beginning of therapy. Results: In the
group with the use of the drug Metaxaz revealed a slight improvement on the 30th day and a significant improvement
in venous cerebral circulation on the 60th day (p<0.05). Conclusion: Against the background of the drug Metaxaz,
there is an improvement in cerebral venous hemodynamics, which allows to recommend it in the complex therapy of
patients with hypertensive encephalopathy of various stages with existing venous cerebral dysgemia.