THE MORPHOLOGY OF THE LYMPH NODES IN INTRAUTERINELY ACQUIRED IMMUNODEFICIENCY IN CHILDREN WHO DIED FROM NEONATAL SEPSIS

Abstract

To identify morphological and morphometric changes in the lymph nodes in immunodeficiencies
acquired in the prenatal and postnatal periods in children who died from neonatal sepsis. Material and Methods:
Paratracheal and mesenteric lymph nodes taken during autopsy in 28 neonatal neonatal neonatal infants
who underwent postmortem diagnosis of thyroid and postnatal immunodeficiency were taken during autopsy.
Results: In case of intrauterinely acquired immunodeficiency, the main morphofunctional zones of the peripheral
organs of immunogenesis are immature, hypoplastic due to underpopulation with lymphocytes. When secondary
immunodeficiencies in the lymph nodes, changes occur depending on damage to the cellular or humoral immunity in
the form of emptying the corresponding structural and functional areas, replacing them with reticular and connective
tissue, as well as the absence of activation of lymphocytes and light reproduction centers. Conclusions: In neonatal
neonatal deaths, secondary immunodeficiency’s manifest themselves in two forms: intrauterinely acquired and
acquired in the early postnatal period. In the latter case, the main morphofunctional zones of the peripheral organs of
immunogenesis are immature, hypoplastic due to underpopulation of lymphocytes.