INDIVIDUAL PREDICTION OF THE DEVELOPMENT OF CERVICAL INTRAEPITHELIAL NEOPLASIA IN WOMEN TO MEDICAL AND SOCIAL RISK FACTORS

Abstract

Objective: The study of medical and social risk factors for the development of cervical pathology and the development
of models for predicting the likelihood of developing a disease in order to identify it in time and prescribe
adequate therapeutic and preventive measures. Material and methods: The study was carried out as part of the research
work of the Department of Obstetrics and Gynecology No. 2 of the Tashkent Medical Academy. The main group
consisted of 226 patients with a clinically and cytologically confirmed diagnosis of CIN; the comparison group included
165 women without clinical signs of CIN. Results: Using the methods of mathematical statistics, the significance was
studied and the leading medical and social risk factors were identified, based on which, using the logistic regression
equation, a mathematical model was developed that allows predicting at an individual level the likelihood of developing
cervical intraepithelial neoplasia. Testing results confirmed the effectiveness of the developed model. Conclusions:
It is proposed to use the identified risk factors and the results of prognostic modeling when conducting preventive
examinations in order to identify patients with a high risk of developing cervical pathology and prescribing preventive
treatment and preventive measures to them.