CHANGES IN MELATONIN CONCENTRATION DEPENDING ON THE SEVERITY OF CHRONIC CEREBRAL ISCHEMIA AND SEASONALITY

Authors

  • Z.I. Adambayev Department of Neurology, Medical Psychology and Psychotherapy Urgench branch of Tashkent Medical Academy
  • M.M. Yakubova Department of Neurology and Medical Psychology Tashkent Medical Academy
  • R.Sh. Olmosov Department of Neurology and Medical Psychology Tashkent Medical Academy

Keywords:

Seasonality, chronic cerebral ischemia, melatonin

Abstract

Chronic cerebral ischemia (CCI) accounts for almost 2/3 of cerebrovascular diseases and causes cognitive impairment. Melatonin deficiency also causes the development of cerebral disorders due to the deterioration of cerebral circulation due to atherosclerotic damage to cerebral vessels and degenerative processes of nervous tissue. In our article, we studied the changes in melatonin concentration depending on the severity of chronic cerebral ischemia and seasonality. 80 patients with CCI were examined. The mean age of the patients was 57.8±11.4 years. Patients were divided into 3 groups depending on the stage of CCI disease and the date of collecting blood serum. It is determined that as the stage of the disease increases, the concentration of melatonin in patients decreases. The lowest concentration was in summer, and the highest concentration was determined in winter

Author Biographies

Z.I. Adambayev, Department of Neurology, Medical Psychology and Psychotherapy Urgench branch of Tashkent Medical Academy

DSc, docent, Department of Neurology, Medical Psychology and Psychotherapy Urgench branch of Tashkent Medical Academy, Urgench. Uzbekistan, e-mail: zufargms@mail.ru

M.M. Yakubova, Department of Neurology and Medical Psychology Tashkent Medical Academy

DSc, professor, Department of Neurology and Medical Psychology Tashkent Medical Academy, Tashkent.Uzbekistan, e-mail: marhamat62@mail.ru

R.Sh. Olmosov, Department of Neurology and Medical Psychology Tashkent Medical Academy

Basically doctorate, Department of Neurology and Medical Psychology Tashkent Medical Academy, Tashkent.Uzbekistan, e-mail: ravshan_uz.99@mail.ru

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Published

2023-10-24

How to Cite

Adambayev, Z., Yakubova, M., & Olmosov, R. (2023). CHANGES IN MELATONIN CONCENTRATION DEPENDING ON THE SEVERITY OF CHRONIC CEREBRAL ISCHEMIA AND SEASONALITY . JOURNAL OF EDUCATION AND SCIENTIFIC MEDICINE, 2(4), 45-48. Retrieved from https://journals.tma.uz/index.php/jesm/article/view/636

Issue

Vol. 2 No. 4 (2023): JESM 2023 #4 (Vol.2) Special issue

Section

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