NEUROINFLAMMATORY MECHANISMS IN HEMORRHAGIC STROKE: focus on the background

Abstract

The scientific review substantiates the role of leukocytes and microglia in the pathogenesis of inflammation in the ischemic brain. Initial neuronal damage occurs within minutes of ischemia, while the inflammatory response that contributes to the progression of the pathology can last from several days to several months. Attention is focused on the fact that the migration of neutrophils into the brain parenchyma and their secretion of proteases is one of the main causes of the death of neurons and glia during reperfusion and delayed brain damage.