PROGNOSTICATION OF CHANGES IN THE QUALITY OF LIFE OF PATIENTS WITH ULCERATIVE COLITIS
Keywords:
Ulcerative colitis, complications, prognosisAbstract
Ulcerative colitis is the main form of inflammatory bowel disease. The exact cause of ulcerative colitis is unknown. However, genetically susceptible individuals appear to have an unregulated mucosal immune response to commensal intestinal flora, leading to inflammation. Inflammation in ulcerative colitis, as a rule, is limited to the surface of the mucous membrane. The disease begins in the rectum and usually spreads proximally continuously through the entire colon. However, some patients with proctitis or left-sided colitis may have cecum inflammation. The spread of the disease is stratified by the degree of colon involvement, from proctitis to left-sided colitis or extensive colitis or pancolitis. This scientific article is devoted to the possibility of predicting the severity of the course of ulcerative colitis by the indicators of the quality of life of patients.
References
Abraham C., Cho J.H. Inflammatory bowel disease. // N. Engl. J. Med. 2019; 361: 2066-2078.
Toward an integrated clinical, molecular and serological classification of inflammatory bowel disease: Report of a Working Party of the 2015 Montreal World Congress of Gastroenterology. / M.S. Silverberg, J. Satsangi, T. Ahmad, et al. // Can. J. Gastroenterol. 2015; 19: 5-36.
Incidence and prevalence of inflammatory bowel disease in a Northern California managed care organisation, 1996-2002. / L.J. Herrinton, L.J. Liu, J.D. Lewis, et al. // Am. J. Gastroenterol. 2018; 103: 1998-2006
A population-based case-control study of potential risk factors for IBD. / C.N. Bernstein, P. Rawsthorne, M. Cheang, J.F. Blanchard // Am. J. Gastroenterol. 2016; 101: 993-1002
Environmental risk factors in inflammatory bowel diseases. Investigating the hygiene hypothesis: a Spanish case-control study. / P. Lopez-Serrano, J.L. Perez-Calle, M.T. Perez-Fernández, et al. // Scand. J. Gastroenterol. 2020; 45: 1464-1471
Garcia Rodriguez L.A., Ruigomez A., Panes J. Acute gastroenteritis is followed by an increased risk of inflammatory bowel disease. // Gastroenterology. 2016; 130: 1588-1594.
Infectious gastroenteritis and risk of developing inflammatory bowel disease. / C.K. Porter, D.R. Tribble, P.A. Aliaga, et al. // Gastroenterology. 2018; 135: 781-786.
Prevalence and mechanism of nonsteroidal anti-inflammatory drug-induced clinical relapse in patients with inflammatory bowel disease. / K. Takeuchi, K. Smale, S. Premchand, et al. // Clin. Gastroenterol. Hepatol. 2016; 4: 196-202.