DEVELOPMENT OF METHODS FOR PREDICTING PERITONITIS IN PATIENTS WITH ACUTE ADHESIVE INTESTINAL OBSTRUCTION

// Collection of abstracts of the scientific and practical conference «Current Problems of Surgical Soft Tissue Infections» (2024), Tashkent, October 28

Authors

  • B.Z. Khamdamov Bukhara State Medical Institute
  • D.A. Sapaev Urgench branch of the Tashkent Medical Academy
  • A.A. Eshchanov Khorezm Regional Branch of the Republican Scientific and Practical Center for Emergency Medical Care
  • D.L. Kurbanbaeva Urgench branch of the Tashkent Medical Academy
  • Zh.L. Babadzhanov Urgench branch of the Tashkent Medical Academy

Abstract

In acute intestinal obstruction complicated by peritonitis, lipid peroxidation and phospholipase activity were increased to a greater extent than in the uncomplicated form of ileus. The level of diene conjugates in the second group increased relative to the norm during the entire follow-up period by 57.4, 110.4, 89.6 and 60.2% (p<0.05), respectively. 28.5, 30.8 and 26.4% (p < 0.05), respectively. Analysis of studies of lipid metabolism in patients with acute intestinal obstruction shows that, regardless of the form of ileus, a significant intensification of membrane lipid peroxidation and activation of phospholipase A2 occurs at the earliest stages of follow-up before surgery. Moreover, in patients whose acute intestinal obstruction was complicated by peritonitis, these pathological processes were more pronounced. This significantly aggravated the course of the early postoperative period, including an increase in the severity of the endogenous intoxication syndrome.

Author Biographies

D.A. Sapaev, Urgench branch of the Tashkent Medical Academy

Urgench branch of the Tashkent Medical Academy, Urgench, Uzbekistan, e-mail: dilshad.sapayev@mail.ru

D.L. Kurbanbaeva, Urgench branch of the Tashkent Medical Academy

D.L. Kurbanbaeva

Urgench branch of the Tashkent Medical Academy, Urgench, Uzbekistan, e-mail: dilnozakurbanbaeva7001@gmail.com

Zh.L. Babadzhanov, Urgench branch of the Tashkent Medical Academy

Zh.L. Babadzhanov

Urgench branch of the Tashkent Medical Academy, Urgench, Uzbekistan, e-mail: jasurbek_babadjanov@mail.ru

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Published

2024-10-28

How to Cite

Khamdamov, B., Sapaev, D., Eshchanov, A., Kurbanbaeva, D., & Babadzhanov, Z. (2024). DEVELOPMENT OF METHODS FOR PREDICTING PERITONITIS IN PATIENTS WITH ACUTE ADHESIVE INTESTINAL OBSTRUCTION : // Collection of abstracts of the scientific and practical conference «Current Problems of Surgical Soft Tissue Infections» (2024), Tashkent, October 28. JOURNAL OF EDUCATION AND SCIENTIFIC MEDICINE, 2(5), 21-22. Retrieved from https://journals.tma.uz/index.php/jesm/article/view/871

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