Keywords
Purulent infection
antiseptics
local treatment of purulent wounds
antiseptics
local treatment of purulent wounds
How to Cite
Okhunov, A. (2023). THE RATIONALE FOR THE CHOICE OF ANTISEPTICS IN THE TREATMENT OF OSTEOARTICULAR PURULENT INFECTION. JOURNAL OF EDUCATION AND SCIENTIFIC MEDICINE, 2(3), 109-112. Retrieved from https://journals.tma.uz/index.php/jesm/article/view/644
Abstract
Polymeric antiseptics from the group of polyhexamethylene guanidines prevent the formation of microbial biofilms and have an antitoxic effect. These antiseptics, including in combination with complexesfrom the bisphosphonate group and Unitiol, inhibit metallo-beta-lactamase and beta-lactamase of multidrug-resistant gram-negative bacteria while enhancing the effect of carbapenems and cephalosporins. The composition based on high-molecular-weight polyvinylpyrrolidone, amikacin and dioxidine has a prolonged effect, antitoxic properties, the ability to localize the infectious focus and impart antimicrobial activity to the tissues surrounding the wound.
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